Febuxostat Powder Drug Treat Chronic Gout and Hyperuricemia

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Buy Febuxostat Powder Drug Treat Chronic Gout and Hyperuricemia Online

 

Febuxostat Specification

Produktname: Febuxostat
CAS: 144060-53-7
Natural/Synthetic: Synthetic
Extraction source: A crystal form
Niveau: Pharmazeutische Klasse
Inhalt: 99%
Aussehen: weißes Puder
Verpackung: 1KG/aluminum foil bag
Ingredients: 2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid
Physical and chemical properties: white or almost white powder; no smell, no taste. This product is dissolved in acetonitrile, acetone, methanol
Kategorie: Pharmazeutische Rohstoffe
Industry: Pharmaceuticals
Feld: Anti gout drugs
Deferred products: febuxostat tablets, capsules
Application: Chronic hyperuricemia for the treatment of gout
Usage and dosage: once a day, 80mg once, and take it with food. After 2 zu 4 wöchiger Behandlung, if the serum uric acid value is higher than 6 mg/dL (357 μmol/L), increase the dose to 120 mg/day.

 

Febuxostat Certificate of Analysis

Produktname Febuxostat
CAS-Nr. 144060-53-7 äußere Verpackung Foil bag
Produktionsdatum 2018.2.10 Haltbarkeit 2020.2.9
Standard, der Unternehmensstandard
Elemente der Analyse Spezifikation Ergebnisse
Aussehen White to almost white crystalline powder, geruchlos weißes kristallines Pulver, geruchlos
Löslichkeit Easily soluble in N,N-Dimethylformamide, soluble in Dimethyl sulfoxide. Sparingly soluble in Chloroform.Sligt soluble in methanol, practically insoluble in water Konform
m.p. 207℃~211℃ 207.5℃~208.5℃
Identifizierung Konform Konform
ImpurityⅠ NMT0.1% N.D.
ImpurityⅡ NMT0.1% N.D.
ImpurityⅢ NMT0.1% N.D.
ImpurityⅣ NMT0.1% 0.02%
Water ≤2.0% 0.5%
Glührückstand ≤0.1% 0.02%
Schwermetalle ≤20ppm Konform
Ethanol ≤5000ppm 23ppm
Tetrahydrofuran ≤720ppm N.D.
N-hexane ≤290ppm N.D.
N,N-Dimethylformamide ≤880ppm N.D.
Dichloromethane ≤600ppm 24ppm
Probe 98.0%~102.0%(Calculated as anhydrous basis) 99.2%
Löslichkeit Easily soluble in N,N-Dimethylformamide, soluble in Dimethyl sulfoxide. Sparingly soluble in Chloroform.Sligt soluble in methanol, practically insoluble in water Konform
m.p. 207℃~211℃ 207.5℃~208.5℃
Identifizierung Konform Konform
ImpurityⅠ NMT0.1% N.D.
ImpurityⅡ NMT0.1% N.D.
ImpurityⅢ NMT0.1% N.D.
ImpurityⅣ NMT0.1% 0.02%
Water ≤2.0% 0.5%
Glührückstand ≤0.1% 0.02%
Schwermetalle ≤20ppm Konform
Ethanol ≤5000ppm 23ppm
Tetrahydrofuran ≤720ppm N.D.
N-hexane ≤290ppm N.D.
N,N-Dimethylformamide ≤880ppm N.D.
Dichloromethane ≤600ppm 24ppm
Probe 98.0%~102.0%(Calculated as anhydrous basis) 99.2%
Schlussfolgerung Qualifizierte

 

Febuxostat Common Side effects

The adverse effects associated with febuxostat therapy include nausea, diarrhea, arthralgia, headache, increased hepatic serum enzyme levels and rash.

 

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