Phentolamine Mesilate Powder | CAS 65-28-1 | Nonselective a-adrenergic blocking drug

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Buy Nonselective a-adrenergic blocking drug Phentolamine Mesilate Powder (CAS 65-28-1)

 

Phentolamine Mesilate Details

Alias: VASOMAX;phentolaminemethanesulphonate; phentolamine methanesulfonate; Phentolamine methanesulfonate salt; phentolamine mesilate
CAS: 65-28-1
EINECS-Nummer: 200-604-6
Formel: C18H23N3O4S
MW: 377.4579
Schmelzpunkt: 180-182 ℃
Boiling point: 551 ° C at 760 mmHg
Flash Point: 287 ° C
Water-soluble: 50 mg / mL
Vapor Pressure: 9.48E-13mmHg at 25 ° C
Aussehen: white powder

 

What is Phentolamine Mesilate?

Phentolamine mesylate (OraVerse), a nonselective a-adrenergic blocking drug, is the first therapeutic agent marketed for the reversal of soft-tissue anaesthesia and the associated functional deficits resulting from an intraoral submucosal injection of a local anaesthetic containing a vasoconstrictor.

 

Phentolamine Mesilate Certificate of Analysis

Standard, der USP 30
Elemente der Analyse Spezifikation Ergebnisse
Apearance weißes kristallines Pulver Konform
Identifizierung UND. UV. RF value Konform
Trocknungsverlust Not more than 0.5% 0.18%
Glührückstand Not more than 0.1% 0.06%
Sulfate Not more than 0.2% 0.11%
Chromatographic purity Total: not more than 1.0% 0.55%
Chromatographic purity Individual: not more than 0.5% 0.19%
Probe Between 98.0% und 102.0% 99.40%
Schlussfolgerung Qualifizierte

 

Phentolamine Mesilate Usage

Prevention or control of hypertensive episodes in patients with pheochromocytoma (excluding OraVerse ); pharmacologic test for pheochromocytoma (not method of choice) (excluding OraVerse ); prevention and treatment of dermal necrosis and sloughing following IV administration or extravasation of norepinephrine (excluding OraVerse ); reversal of soft-tissue anesthesia (ie, anesthesia of lip and tongue) ( OraVerse only).

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