Desonide Powder | CAS 638-94-8 | Raw API Topical Corticosteroids

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Desonide Powder | CAS 638-94-8 | Raw API Topical Corticosteroids

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CAS NO.: 638-94-8
Assay: 99%
Molecular Formula:C24H32O6
Molecular Weight:416.51
Usage: With acetal-based adrenal cortex hormones

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Buy Topical Corticosteroids Drugs Desonide Raw API Powder (CAS 638-94-8)

 

Desonide Description

Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.

 

Desonide Certificate of Analysis

Standard adopted USP38
Items of analysis Specification Results
Description white powder or crystal. white crystalline powder
Solubility Soluble in chloroform,sparingly in ethanol and in acetone ,practically insoluble in water complies
Identification A:IR B:HPLC complies
Assay(HPLC) 98.0%~102.0% 99.8%
16α-Hydroxyprednisolone not more than 0.15% n.d
Prednisolone not more than 0.15% 0.05%
Desonide glyoxal not more than 0.50% 0.26%
Deoxyprednisolone-16-ene not more than 0.50% n.d
Sum desonide glyoxal and deoxyprednisolone-16-en not more than 0.50% 0.26%
Dihydrodesonide not more than 0.50% 0.26%
Epoxydesonide not more than 0.50% n.d
Sum of dihydrodesonide and epoxydesonide not more than 0.50% 0.26%
Bromodesonide not more than 0.15% n.d
Acetyldesonide Acetyldesonide 0.05%
Any other impurity not more than 0.10% 0.01%
Total impurities not more than 1.00% 0.59%
Loss on drying ≤ 0.5% 0.09%
Optical rotation +104.0°~+ 110.0° +105.9°
Dichloromethane not more than 600ppm complies
Methanol not more than 3000ppm complies
Pyridine not more than 200ppm complies
Acetone not more than 5000ppm complies
Particle size 100%≤30 microns complies
Residue on ignition ≤0.1% 0.03%
Conclusion Qualified

 

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