Spironolactone (Aldactone) Poudre | NO CAS 52-01-7 | AR Antagonist

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Spironolactone (Aldactone) Poudre | NO CAS 52-01-7 | AR Antagonist

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Synonyme: Aldactone; Antisterone; spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,
17-beta- carbolactone
NO CAS: 52-01-7
EINECS: 200-133-6
MF: C24H32O4S

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Buy AR Antagonist Spironolactone (Aldactone) Poudre (NO CAS 52-01-7) Online

 

Spironolactone Description

Spironolactone is a potent and direct antagonist of the AR, blocking androgens like testosterone from binding to and activating the receptor. The AR antagonism of spironolactone mostly underlies its antiandrogen activity and is responsible for its therapeutic benefits in the treatment of androgendependent conditions like acne, hirsutism, and pattern hair loss and its usefulness in hormone therapy for transgender women. en outre, the AR antagonism of spironolactone is involved in its feminizing side effects like gynecomastia in men.

 

Spironolactone Quick Details

Synonyme: Aldactone;Antisterone;spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,
17-beta- carbolactone
NO CAS: 52-01-7
EINECS: 200-133-6
MF: C24H32O4S
MW: 416.5735
Densité: 1.24g / cm3
Point de fusion: 198-207 ºC (dec.)
Boiling point: 597 ° C at 760 mmHg
Flash Point: 302.2 ° C
Water-soluble: practically insoluble
Vapor Pressure: 3.24E-14mmHg at 25 ° C
Rotation spécifique -37 ° (c = 1, CHCl3)
Spironolacton Water-soluble practically insoluble
Essai: 99%
Apparence: fine poudre cristalline blanche ou presque blanche

 

Spironolactone Certificate of Analysis

Nom du produit Spironolactone
CAS No. 52-01-7 Emballage externe 1KG / sac
Date de production 2018.09.02 Durée de conservation 2022.09.01
Norme adoptée EP7/USP39
Éléments d’analyse Spécification du Résultats
Apparence white or yellowish-white powder. white powder
Solubility practically insoluble in water, soluble in ethanol(96 per cent). conforme
Identification A/B/C Meet the requirements conforme
Rotation spécifique 41 to − 46°(EP) 41 to − 45°(USP) -43°
Perte sur le séchage Not more than 0.5% 0.08%
Sulfated ash Not more than 0.1% 0.03%
Impurity AImpurity C Not more than 0.2% N.D
Impurity FImpurity E Not more than 0.3% N.D
Impurity D Not more than 0.15% N.D
Impurity I Not more than 0.5% N.D
Other arbitrary unknown impurities Not more than 0.1% conforme
impuretés totales Not more than 0.7% 0.15%
ordinary impurities(USP) Not more than 2.0% 0.05%
Free thiol compounds(EP) Not more than 0.05 mL conforme
Free mercapto compounds(USP) Not more than 0.1mL conforme
Chromium(EP) Not more than 50ppm conforme
Essai 97.0%~103.0%(USP);97.5-102%(EP) 99.9%(USP);100.1%(EP)
Fineness 95%Not more than 20 μm conforme
Conclusion Qualifié

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