Furosemide (Lasix) Powder (CAS 54-31-9) | Pharmaceutical Raw Materials

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Furosemide (Lasix) Powder (CAS 54-31-9) | Pharmaceutical Raw Materials

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MF:C12H11ClN2O5S
MW:330.74
CAS:54-31-9
Appearance:white powder
Purity:99.56%
Standard:USP standard

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Buy USP Standard China Pharmaceutical Raw Materials Furosemide (Lasix) Powder (CAS 54-31-9)

 

Furosemide (Lasix) Application

Furosemide is a potent diuretic (water pill) that is used to eliminate water and salt from the body.

Furosemide is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.

Furosemide is also used to treat high blood pressure (hypertension).

 

Furosemide (Lasix) Certifiate of Analysis

Product name furosemide
CAS No. 54-31-9 Outer Packing 25KG/DRUM
Production date JAN.2019 Shelf life JAN.2023
Standard adopted USP37
Items of analysis Specification Results
description white or almost white crystalline powder white crystalline powder
solubility practically insoluble in water and methylene chloride,soluble in acetone,sparingly soluble in ethanol(96%),slightly soluble in ether,it dissolves in dlute solution of alkali hydroxide. complies
identification    
A Infrared absorption spectrum should be concordant with IR spectrum of Furosemide CRS complies
B ultra violate and visible absorption spectrophotometer(ratio 0.52-0.57) complies
melting point 210℃ 210℃
residue on ignition NMT 0.10% W/W 0.06% W/W
heavy metals NMT 20 ppm less than 20 ppm
chloride NMT 200ppm less than 200ppm
sulphates NMT 300 ppm less than 300ppm
loss on drying(hot air oven at 105℃ for 3 hrs) NMT 0.50% W/W 0.24%
Related substance by HPLC    
impurity A NMT 0.25% less than 0.25%
impurity B NMT 0.25% less than 0.25%
impurity C NMT 0.25% less than 0.25%
impurity D NMT 0.25% less than 0.25%
impurity E NMT 0.25% less than 0.25%
total impurity NMT 0.50% 0.12%
any individual impurity NMT 0.10% 0.05%
assay 98%-101% on dry basis 99.56%
residual solvent iso propyl alcohol:not more than 5000ppm 263 ppm
Conclusion Qualified

 

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