Hydrochlorothiazide Powder Diuretic Medication Pharmaceutical Raw Materials (CAS 58-93-5)

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Buy Diuretic Medication Hydrochlorothiazide Powder Diuretic Pharmaceutical Raw Materials (CAS 58-93-5)


Hydrochlorothiazide Quick Details

Synonyms: 6-Chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
CAS: 58-93-5
EINECS Number: 200-403-3
Formula: C7H8ClN3O4S2
MW: 297.7391
Density: 1.693g / cm3
Melting point: 273-275 ℃
Assay: 99%
Appearance: White or almost white fine crystalline powder


Hydrochlorothiazide Description and Application

Hydrochlorothiazide is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up. Other uses include diabetes insipidus, renal tubular acidosis, and to decrease the risk of kidney stones in those with high calcium level in the urine.

For high blood pressure it is often recommended as a first line treatment. HCTZ is taken by mouth and may be combined with other blood pressure medications as a single pill to increase the effectiveness.


Hydrochlorothiazide Certificate of Analysis

Product name  
CAS No. 58-93-5 Outer Packing 25/bag
Production date 2017.5.8 Shelf life 2021.5.8
Standard adopted In-house specifications
Items of analysis Specification Results
Characters White or praceically white,practically odorless,crystalline powder Complies
Identification A.IR spectrum conforms to Standard .B.UVspectrum conforms to Standard Complies
Loss on Drying NMT0.5% 0.05%
Residue on lgnition NMT0.1% 0.02%
Chlorides NMT0.035% Complies
Selenium NMT0.003% Complies
Heavy Metals NMT0.001% Complies
Residual Solvents LOD NMT0.5% 0.05%
Assay Between 98.0%and 102.0%(Calculated on the dried basis) 100.1%
Residual Formaldehyde NMT15ppm 5ppm
Benzothiadiazine related componud A ≤1.0% 0.14%
Hydrochlorothiazide dimer ≤ 0.5% 0.12%
5-chlorohydrochlorothiazide ≤ 0.5% Not detected
Chlorothiazide ≤ 0.5% Not detected
Single unknown impurity ≤ 0.10% Not detected
Total unknown impurities ≤ 0.5% Not detected
Total other impurities excluding benzothiadiazine related compound A ≤ 0.9% 0.12%
Total impurities ≤ 1.5% 0.26%
Conclusion Qualified

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