Leflunomide Powder Immunosuppressive Disease-Modifying Antirheumatic Drug (DMARD)

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  • Specifications

Buy Leflunomide Powder Immunosuppressive Disease-Modifying Antirheumatic Drug (DMARD) Online

 

Leflunomide Specification

Product Name: Leflunomide
CAS: 75706-12-6
Standard: Enterprise Standard
Natural/Synthetic: Synthetic
Level: Pharmaceutical grade
Content: 99%
Appearance: white powder
Packing: 1kg/aluminum foil bag
Category: Pharmaceutical Raw Materials
Industry: Pharmaceuticals
Field: Anti-inflammatory analgesics
Deferred products: Leflunomide tablets
Use: Hydrogenated orotic acid dehydrogenase inhibitors, with immunosuppressive and anti-inflammatory effects, for the treatment of active rheumatoid arthritis in adults.
Usage and dosage: Adult rheumatoid arthritis: Oral. Due to the long half-life of leflunomide, it is recommended to administer at intervals of 24 hours. In order to rapidly reach the steady state plasma concentration, refer to the foreign clinical trial data and combined with the results of phase I clinical trials, it is recommended that the first three days of starting treatment be given a dose of 50 mg a day, and then a maintenance dose of 10 mg or 20 mg a day should be given. Non-steroidal anti-inflammatory drugs or low-dose corticosteroids may continue to be used during treatment with this drug.

 

What is Leflunomide?

Leflunomide (brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.

 

Leflunomide Test Report

Item Requirement Result
Description White crystals powder White crystals powder
Melting point 165-166°C 165-166°C
Identification IR Identical
Assay ≥99% 99.5%
Heavy metal ≤10ppm ≤10ppm
Loss on drying ≤1.0% ≤1.0%
Ask ≤0.1% ≤0.1%

 

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