Piroxicam Powder Nonsteroidal anti-inflammatory drug NSAIDs

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Buy USP39 Piroxicam Powder Nonsteroidal anti-inflammatory drug NSAIDs Online From China Manufacturer

 

Piroxicam Specification

Product Name: Piroxicam
CAS:36322-90-4
Standard: USP39
Natural/Synthetic: Synthetic
Level: Pharmaceutical grade
Content: 99%
Appearance: slightly yellow powder
Packing: 25KG/cardboard drum
Ingredients: 2-methyl-4-hydroxy-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide; titration
Physicochemical properties: white to yellowish green crystalline powder; odorless, tasteless. This product is soluble in chloroform, slightly soluble in acetone, slightly soluble in ethanol or ether, almost insoluble in water; dissolved in acid, slightly soluble in alkali.
Category: Pharmaceutical Raw Materials
Industry: Pharmaceuticals
Field: Anti-inflammatory analgesics
Deferred products: Piroxicam 20mg tablets
Use: Symptomatic treatment for alleviating the pain and swelling of various arthritis and soft tissue lesions.
Usage and dosage: Oral. Adults commonly used amount: once 20mg, once a day, or once l0mg, 2 times a day. Take after meals. Ingredients: Low-substituted hydroxypropyl cellulose, starch, dextrin, powdered sugar. Carboxymethyl starch, magnesium stearate, coating powder

 

What is Piroxicam?

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful, inflammatory conditions like arthritis. Piroxicam works by preventing the production of endogenous prostaglandins which are involved in the mediation of pain, stiffness, tenderness and swelling.

 

Piroxicam Certificate of Analysis

Product name Piroxicam
CAS No. 36322-90-4 Outer Packing 25KG /drum
Production date 2018.01.15 Shelf life 2021.01.14
Standard adopted USP39
Items of analysis Specification Results
Characteristics A white or slightly yellow,crystalline powder slightly yellow,crystalline powder
Water ≤0.5% 0.002%
Residue on ingition ≤0.3% 0.05%
Heavy metals ≤0.005% <0.005%
Organic volatile impurities Conforms to U.S.P39 Meet the requirements
Solubility vear slightly soluble in water,in dilute acids and in most organics solvents slightly soluble in alcohol and aqueous alkaline solutions Meet the requirements
residual resolver alcohol Meet the requirements
Assay 97-103% 99.7%
Conclusion Qualified

 

Piroxicam Application

It used in the treatment of rheumatoid and osteoarthritis, primary dysmenorrhoea, postoperative pain; and act as an analgesic, especially where there is an inflammatory component.

 

Piroxicam Side effects

Piroxicam side effects include: digestive complaints like nausea, discomfort, diarrhoea and bleeds or ulceration of the stomach, as well as headache, dizziness, nervousness, depression, drowsiness, insomnia, vertigo, hearing disturbances (such as tinnitus), high blood pressure, oedema, light sensitivity, skin reactions (including, albeit rarely, Stevens-Johnson syndrome and toxic epidermal necrolysis) and rarely, kidney failure, pancreatitis, liver damage, visual disturbances, pulmonary eosinophilia and alveolitis.

Compared to other NSAIDs it is more prone to causing gastrointestinal disturbances and serious skin reactions.

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