Phentolamine Mesilate Powder | CAS 65-28-1 | Nonselective a-adrenergic blocking drug

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Buy Nonselective a-adrenergic blocking drug Phentolamine Mesilate Powder (CAS 65-28-1)

 

Phentolamine Mesilate Details

pseudônimo: VASOMAX;phentolaminemethanesulphonate; phentolamine methanesulfonate; Phentolamine methanesulfonate salt; phentolamine mesilate
CAS: 65-28-1
Número EINECS: 200-604-6
Fórmula: C18H23N3O4S
MW: 377.4579
Ponto de fusão: 180-182 ℃
Boiling point: 551 ° C at 760 mmHg
Flash Point: 287 ° C
Water-soluble: 50 mg / mL
Vapor Pressure: 9.48E-13mmHg at 25 ° C
Aparência: white powder

 

What is Phentolamine Mesilate?

Phentolamine mesylate (OraVerse), a nonselective a-adrenergic blocking drug, is the first therapeutic agent marketed for the reversal of soft-tissue anaesthesia and the associated functional deficits resulting from an intraoral submucosal injection of a local anaesthetic containing a vasoconstrictor.

 

Phentolamine Mesilate Certificate of Analysis

norma aprovada USP 30
Itens de análise Especificação Resultados
Apearance pó branco cristalino Conforme
Identificação E. UV. RF value Conforme
Perda ao secar Not more than 0.5% 0.18%
Resíduo de ignição Not more than 0.1% 0.06%
Sulfate Not more than 0.2% 0.11%
Chromatographic purity Total: not more than 1.0% 0.55%
Chromatographic purity Individual: not more than 0.5% 0.19%
Ensaio Between 98.0% e 102.0% 99.40%
Conclusão Qualificado

 

Phentolamine Mesilate Usage

Prevention or control of hypertensive episodes in patients with pheochromocytoma (excluding OraVerse ); pharmacologic test for pheochromocytoma (not method of choice) (excluding OraVerse ); prevention and treatment of dermal necrosis and sloughing following IV administration or extravasation of norepinephrine (excluding OraVerse ); reversal of soft-tissue anesthesia (ie, anesthesia of lip and tongue) ( OraVerse only).

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