Indometacin Powder Non-steroidal Anti-inflammatory Drugs For Pain Relief

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Indometacin Specification

Product Name: Indomethacin
CAS: 53-86-1
Standard: BP
Natural/Synthetic: Synthesis
Content: 98.5%
Appearance: white powder
Packing: 25KG/cardboard drum
Ingredients: 2-Methyl-1-(4-chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acid
Physicochemical properties: white to yellowish crystalline powder; almost odorless, tasteless. This product is dissolved in acetone, slightly soluble in methanol, ethanol, chloroform or ether, very slightly soluble in toluene, almost insoluble in water.
Category: Pharmaceutical Raw Materials
Industry: Pharmaceuticals
Field: Antipyretic and analgesic non-steroidal anti-inflammatory drugs
Down products: Tablets Enteric-coated tablets Controlled-release tablets Capsules Controlled release capsules Suppositories Lusters Creams Gels
Use: Relieve inflammatory pain is obvious, it can be used for acute and chronic rheumatoid arthritis, gouty arthritis and cancer pain; can also be used for bursitis, tenosynovitis and capsulitis
Dosage: Ordinary tablet 25mg, 2 or 3 times a day, at meals or after meals. When necessary, it can be increased to 100 to 150 mg per day, 3 to 4 times per day; oral controlled-release capsules 25 mg, 2 times per day, and if necessary, it can be increased to 50 mg twice daily. Treatment of acute gout: Adults take 50 mg orally 3 to 4 times a day

 

Indomethacin Certificate Of Analysis

Product name INDOMETHACIN
CAS No. 53-86-1 Outer Packing 25KG
Production date 2018.01.02 Shelf life 2023.01.01
Standard adopted BP2013
Items of analysis Specification Results
Description White or yellow crystalline powder , Pratically insoluble in water, sparingly Soluble in alcohol Complies
A. Melting point 158℃~162℃ 160℃~161℃
B: Absorption at 318nm 170~190 184
C Conforms to the requirement Conforms
D Conforms to the requirement Conforms
E Conforms to the requirement Conforms
Heavy metals ≤20ppm Pass
Related substances(TLC) ≤0.5% 0.04%
Loss on drying ≤0.5% 0.20%
Sulphated Ash ≤0.1% 0.03%
Assay 98.5~100.5% 99.7%
Any Individual Impurity ≤0.10% 0.05%
Sum of all Impurity ≤0.30% 0.20%
Conclusion Qualified

 

What is Indomethacin?

Indometacin (indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does this by inhibiting cyclooxygenase, an enzyme that catalyzes the production of prostaglandins.

 

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